| 26. STANDARD LINE OF TREATMENT | |
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PRESUMPTIVE TREATMENT (PT):
Age in Low Risk Area High Risk Area Years - —————————————————————————————————————————- Chloroquine(mg) chloroquine(mg) primaquine (mg)
Day1 Day1 Day2 Day3 Day1
0 –1 75 75 75 37.5 - 1- 4 150 150 150 75 7.5 4 – 8 300 300 300 150 15.0 8 – 14 450 450 450 225 30.0 > 14 600 600 600 300 45.0
RADICAL TREATMENT (RT)
Age in P.vivax P.falliparum Years —————————————————————————————- Chloroquine (mg) Primaquine (mg) Chloroquine (mg) primaquine (mg)
(mg) Day1 Day1 Day2 Day3 One day treatment only
0 –1 75 - - - 75 - 1- 4 150 5 5 2.5 150 10.0 4 – 8 300 10 10 5 300 20.0 8 – 14 450 20 20 10 450 30.0 > 14 600 30 30 15 600 45.0
STANDARD TREATMENT OF LEPRUSY For paucibacillary patients (PB) :
Adult children ——————————————- 6-14yrs. Upto 5 yrs.
Monthly treatment
Day 1 Rifampicin 600 mg 450 mg 300 mg Dapsone 100 mg 50 mg 25 mg Daily treatment Day 2 –28 Dapsone 100 mg 50 mg 25 mg
Duration of treatment 6 months course to be taken within a maximum period of 9 months .
For multibacillary patients (MB):
Adult children ——————————————- 6-14yrs. Upto 5 yrs. Monthly treatment Day 1 Rifampicin 600 mg 450 mg 300 mg Clofazimine 300 mg 150 mg 100 mg Dapsone 100 mg 50 mg 25 mg Daily treatment Day 2 –28 Clofazimine 50 mg * 50 mg * * 25 mg Dapsone 100 mg 50 mg 25 mg Duration of treatment 12 months course to be taken within a maximum period of 18 months . ———————————————————————- * - on alternative days ; ** - twice a week.
For Single lesion paucibacillary patients (SLPB) :
Adult Children 6 –1 4 yrs.
Single dose Rifampicin 600 mg 300 mg Ofloxacine 400 mg 200 mg Minocycline 100 mg 50 mg
STANDARD TREATMENT OF TUBERCULOSIS:
ESSENTIAL Recommended Dose Anti – TB Drug ————————————————————————————— Daily Intermittent ———————————————————— 3 times/week 2 times/week Isoniazid 5 mg / kg 10 mg/kg 15 mg/kg (4-6 mg/kg) (8 – 12 mg/kg) (13 –15 mg/kg). Rifampicin 10 mg / kg 10 mg/kg 10 mg/kg (8-12 mg/kg) (8 – 12 mg/kg) (8 –12 mg/kg). Pyrazinamide 25 mg / kg 35 mg/kg 50 mg/kg (20-30 mg/kg) (30 – 40 mg/kg) (40 –60 mg/kg). Streptomycin 15 mg / kg 15 mg/kg 50 mg/kg (12-18 mg/kg) (12 –18mg/kg) (12 –18 mg/kg). Ethambutol 15 mg / kg 30 mg/kg 45 mg/kg (15-20 mg/kg) (25 – 35 mg/kg) (40 –50 mg/kg).
Treatment of Tuberculosis in children:
2 HRZ/4 HRZ For primary TB and TB 2 EHRZ/4 HR Lymphadenitis 1 5
2 EHRZ/10 HR TBM and miliary TB and disseminated TB along with steroids 1 5 9 HR primary complex without any other Systemic complication.
SEXUALLY TRANSMITTED DISEASE TREATMENT OF GONORRHOEA: Ciprofloxacin 500 mg orally in a single dose (contraindicated in pregnancy). TREATEMETN OF CHLAMYDIA INFECTION : Doxycycline 100 mg orally 2 times daily for 7 days or Erythromycin 500 mg orally 4 times daily for 7 days (pregnant woman). TREATMENT FOR TRICHOMONIASIS AND BACTERIAL VAGINOSIS Metronidazole 400 mg orally twice daily for 7 days or 2 gm orally as a single dose. Note : metronidazole should not be given during the first trimester of pregnancy. TREATMENT OF CANDIDIASIS Clotrimazole 200 mg intravaginally once daily for 3 days. TREATMENT FOR SYPHILIS : Benzathing penicillin 2.4 million units IM in 2 injections (equally divided after intradermal sensitivity test for penicillin. For men and non-pregnant women sensitive to penicillin : Doxycycline 100 mg orally 2 times daily for 15 days. For pregnant women sensitive to penilillin. Erythromycin stearate 500 mg orally 4 times daily for 15 days advice those women to bring the child within 7 days of birth for screening). TREATMENT FOR CHANCROID Erythromycin stearate 500 mg orally 4 times daily for 7 days or ciprofloxacin 500 mg orally as a single dose (do not give to pregnant women). TREATMENT FOR HERPES First episode : Acylovir 200 mg orally 5 times daily for 7 days. Recurrent episode : acyclovir 200 mg orally 5 times daily for 5 days. ACUTE RESPIRATORY INFECTIONS: Case management: · Infants aged 0-2 months, with a respiratory rate of 60 per minute or more. Co-trimoxazole (paediatric) 3 tablet twice a day for 5 days. · Children 2-12 months of age with respiratory rate of 50 per minute or faster, with no signs of respiratory distress (e.g. chest in drawing). Co- trimoxazole (paediatric) 2 tablets twice a day for 5 days. · Children 1 – 5years of age with a respiratory rate of 40 per minute or greater, and no signs of respiratory distress. Co-trimoxazole (paediatric) 3 tablets twice daily for 5 days. SEVERE PNEUMONIA · Refer URGENTLY to hospital · Give first dose antibiotic (co-trimoxazole). · Treat fever, if present (if referral is not feasible, treat with antibiotic and follow closely). · Keep the baby warm. PNEUMONIA · Advise mother to give home care · Give antibiotic (co-trimoxazole). · Treat fever, if present · Advise mother to return with child in 2 days for reassessment or earlier if the child is getting worse. · Keep the baby warm. NO PNEUMONIA: COUGH OR COLD · If coughing more than 30 days, refer for assessment · Assess and treat other problems. · Advise mother to give home care. · Treat fever, if present. (Reassess in 2 days a child who is taking an antibiotic for pneumonia.) TREATMENT OF DIARRHOEAL DISEASES: 1. TREATMENT DIARRHOEA AT HOME (Plan A) 1. Give the child more fluid then usual to prevent dehydration 2. Give the child plenty of food to prevent malnutrition. 3. Take the child to the HEALTH WORKER. If the child does not get better in 3 days or develops any of the following. · Many watery stools eating or drinking poorly. · Repeated vomiting fever · Marked thirst blood in the stool THE CHILD SHOULD BE GIVEN ORS SOLUTIONS AS PER THE FOLLOWING SCHEDULE:
Age Amount of ORS to give Amount of ORS to provide After each loose stool for use at home
Less than 24 months 50 – 100 ml 500 ml/day. 2 upto 10 yrs. 100 – 200 ml 1000 ml/day. 10 years or more As much as wanted 2000 ml/day.
II.TREATMENT OF DEHYDRATION (Plan B) APPROXIMATE AMOUNT OF ORS SOLUTION BE GIVEN IN THE FIRST 4 HOURS:
Age Less than 4 4 – 11 12 –23 2 – 4 5 – 14 15yrs. Months months months years years or older
Wt. Less than 5 kg. 5 –7.9 kg 8 –10.9kg 11 –15.9 kg 16 –29.9kg 30 kg or
In ml. 200 –400 400-600 600-800 800-1200 1200-2200 2200-4000
· Use the patient age only you do not know the weight . The approximate amount of ORS required (in ml) can also be calculated by multiplying the patient’s weight(in Kg) times 75. · if the child wants more ORS than shown, give more. · Encourage the mother to continue breast feeding. · For infants under 6 months who are not breast fed, also give 100 –200 ml clean water during this period. III . TREAT SEVERE DEHYDRATION (Plan C) Start IV fluids immediately. If the patient can drink , give ORS by mouth while the drip is set up. Give 100 ml /kg ringer’s lactate solution (or, if not available, normal saline), divided as follows :
Age first give The give 30 ml/kg in : 70 ml /kg in infants 1 hours 5 hours. (under 12 months) older 30 minutes 2.5 hours. Repeat once if radial pulse is still very weak or not detectable. Reassess the patient every 1 – 2 hours . If hydration is not improving, give the IV drip rapidly.
Also give ORS (about 5 ml/kg/hour) as soon as the patient can drink :
usually after 3 –4 hours After 6 hours (infants) or 3 hours (older patients), evaluate the patient using the assessment chart. Then choose the appropriate plan (A,B,C) to continue treatment.
Treatment of Dysentery: ( Diarrhoea with blood in stool ) | Treat with co- trimoxazole | Treat fever with paracetamol | Give ORS and early feeding | Child well or definitely improving | |
Yes NO | | Continue therapy monitor weight response | | Monitor weight response if no response Refer 1.Co –trimoxazole : Adult: 2 tab. (160 mg. TMP + 800 mg SMX) 2 times a day x 5 days Children: 5 mg TMP+25 mg of SMX per kg 2 times a day 5 days Treatment of cholera: 1. Doxycycline 100 mg tab/cap. Adult : 300 mg single dose. Children: not used for children below 12 years. 2. Co-trimoxazole : Adult: 2 tab. (160 mg TMP + 800 mg SMX 2 times a days 3. Children: pediatric tab. (20 mg TMP + 100 mg SMX). 5 mg of TMP+25mg of SMX /kg) 2 times a day x 3 days Syrup (40 mg TMP+200 mg SMX in 5 ml). 3. Furazolidone 100 mg tab. Adult: 100 mg 4 times a day x 3 days. Children : 1.25 mg/kg 4 times a day x 3 days. Treatment of parasitic diarrhoea : Intestinal Amoebiasis : Metronidazole 200 mg tab. Adult : 400 – 600 mg 3 times a day x 5 days. (10 days for severe disease). Children : 10 mg/kg 3 times a day x 5 days (10 days for severe disease)> Giardiasis : Metronidazole 200 mg tab. Adult : 200 –400 mg 3 times a dayx 5 days. Children : 5 mg/kg 3 times a day x 5 days. |